Nrf2 is a powerful protein that is latent within each cell in the body, unable to move or operate until it is released by an Nrf2 activator. Once released it migrates into the cell nucleus and bonds to the DNA at the location of the Antioxidant Response Element (ARE) which is the master regulator of the total antioxidant system that is available in ALL human cells.
It turns out that a variety of phytonutrients are powerful activators of the Nrf2 pathway. While not necessarily rich in antioxidants, they directly and dramatically amplify our innate ability to produce vast antioxidant protection by signaling our DNA. In this way, specific molecules from Nrf2 activating plant-derived bioactives can trigger the production of thousands of antioxidant molecules, providing far better protection against the cell-damaging effects of free radicals compared to standard antioxidant supplement.
Other NRF2 resources:
Pubmed.gov http://www.ncbi.nlm.nih.gov/pubmed?term=nrf2
Google scholarly NRF2 Articles: http://scholar.google.com/scholar?q=NRF2
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